8 years old greater than or equal to age lesss than or equal to 80 years old, both men or women. <br/ > <br/ >Subject with confirmed severe COVID19 in less than 5 days who meets any of the following criteria <br/ > <br/ >Respiratory distress RRgreater than or equal to 30 times per min <br/ >In resting state finger oxygen saturation lesss than or equal 93 percent <br/ >Oxygenation Index PaO2 to FiO2 lesss than or equal 300 mmHg 1 mmHg equals 0.133kpa in supine position <br/ >Pulmonary imaging shows lesion progression >50% within 24 â?? 48 hours <br/ > <br/ > <br/ >The informed consent signed

8 years old greater than or equal to age lesss than or equal to 80 years old, both men or women. <br/ > <br/ >Subject with confirmed severe COVID19 in less than 5 days who meets any of the following criteria <br/ > <br/ >Respiratory distress RRgreater than or equal to 30 times per min <br/ >In resting state finger oxygen saturation lesss than or equal 93 percent <br/ >Oxygenation Index PaO2 to FiO2 lesss than or equal 300 mmHg 1 mmHg equals 0.133kpa in supine position <br/ >Pulmonary imaging shows lesion progression >50% within 24 â?? 48 hours <br/ > <br/ > <br/ >The informed consent signed

8 years old greater than or equal to age lesss than or equal to 80 years old, both men or women. <br/ > <br/ >Subject with confirmed severe COVID19 in less than 5 days who meets any of the following criteria <br/ > <br/ >Respiratory distress RRgreater than or equal to 30 times per min <br/ >In resting state finger oxygen saturation lesss than or equal 93 percent <br/ >Oxygenation Index PaO2 to FiO2 lesss than or equal 300 mmHg 1 mmHg equals 0.133kpa in supine position <br/ >Pulmonary imaging shows lesion progression >50% within 24 â?? 48 hours <br/ > <br/ > <br/ >The informed consent signed

8 years old greater than or equal to age lesss than or equal to 80 years old, both men or women. <br/ > <br/ >Subject with confirmed severe COVID19 in less than 5 days who meets any of the following criteria <br/ > <br/ >Respiratory distress RRgreater than or equal to 30 times per min <br/ >In resting state finger oxygen saturation lesss than or equal 93 percent <br/ >Oxygenation Index PaO2 to FiO2 lesss than or equal 300 mmHg 1 mmHg equals 0.133kpa in supine position <br/ >Pulmonary imaging shows lesion progression >50% within 24 â?? 48 hours <br/ > <br/ > <br/ >The informed consent signed