inclusion criteria: - willing and able to provide written informed consent - signs and symptoms suggestive of covid-19 infection - laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (sars-cov-2) infection ≤7 days before randomization - currently hospitalized or in an emergency department with planned hospitalization - peripheral capillary oxygen saturation (spo2) <93% on room air at screening

inclusion criteria: - willing and able to provide written informed consent - signs and symptoms suggestive of covid-19 infection - laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (sars-cov-2) infection ≤7 days before randomization - currently hospitalized or in an emergency department with planned hospitalization - peripheral capillary oxygen saturation (spo2) <93% on room air at screening