inclusion criteria: - any gender - age > 18 years on day of signing informed consent - informed written consent for participation in the study - virological diagnosis of sars-cov-2 infection (real-time pcr) - hospitalized due to clinical instrumental diagnosis of pneumonia. - oxygen saturation at rest in ambient air ≤93% or p/f ratio <250 - able to be administered by oral route drugs - patients who receive o2 therapy or who need non-invasive mechanical ventilation - in case of female patients at childbearing potential, they should agree to use highly effective methods of birth control at least till 7 days after the termination of the treatments

inclusion criteria: - any gender - age > 18 years on day of signing informed consent - informed written consent for participation in the study - virological diagnosis of sars-cov-2 infection (real-time pcr) - hospitalized due to clinical instrumental diagnosis of pneumonia. - oxygen saturation at rest in ambient air ≤93% or p/f ratio <250 - able to be administered by oral route drugs - patients who receive o2 therapy or who need non-invasive mechanical ventilation - in case of female patients at childbearing potential, they should agree to use highly effective methods of birth control at least till 7 days after the termination of the treatments