inclusion criteria: - sars-cov2 infection diagnosed by rt-pcr - ct-scan confirmed interstitial pneumonia - hospital admission from less than 24h - p/f ratio >150 mmhg - written informed consent

inclusion criteria: - sars-cov2 infection diagnosed by rt-pcr - ct-scan confirmed interstitial pneumonia - hospital admission from less than 24h - p/f ratio >150 mmhg - written informed consent