- pregnancy - breastfeeding - known severe hepatic impairment - known severe renal impairment - known porphyrias - diabetes mellitus - known g6pd deficiency - known myasthenia gravis - known severe psoriasis - known severe neurological disorders (especially those with a history of epilepsy - may lower seizure threshold)

- pregnancy - breastfeeding - known severe hepatic impairment - known severe renal impairment - known porphyrias - diabetes mellitus - known g6pd deficiency - known myasthenia gravis - known severe psoriasis - known severe neurological disorders (especially those with a history of epilepsy - may lower seizure threshold)