key inclusion criteria: hospitalization for covid-19 infection severe acute respiratory syndrome coronavirus (sars-cov)-2 infection confirmed by polymerase chain reaction (pcr) participant requires supplemental oxygen for pulmonary distress related to covid-19 infection, and has been on supplemental oxygen for no more than 96 hours from time of screening key

key inclusion criteria: hospitalization for covid-19 infection severe acute respiratory syndrome coronavirus (sars-cov)-2 infection confirmed by polymerase chain reaction (pcr) participant requires supplemental oxygen for pulmonary distress related to covid-19 infection, and has been on supplemental oxygen for no more than 96 hours from time of screening key

key inclusion criteria: hospitalization for covid-19 infection severe acute respiratory syndrome coronavirus (sars-cov)-2 infection confirmed by polymerase chain reaction (pcr) cohort 1: participant requires supplemental oxygen for pulmonary distress related to covid-19 infection, and has been on supplemental oxygen for no more than 48 hours. cohort 2: participants will have been on mechanical ventilation for ≤ 24 hours from the time of screening radiographic evidence of pulmonary infiltrates key

key inclusion criteria: hospitalization for covid-19 infection severe acute respiratory syndrome coronavirus (sars-cov)-2 infection confirmed by polymerase chain reaction (pcr) cohort 1: participant requires supplemental oxygen for pulmonary distress related to covid-19 infection, and has been on supplemental oxygen for no more than 48 hours. cohort 2: participants will have been on mechanical ventilation for ≤ 24 hours from the time of screening radiographic evidence of pulmonary infiltrates key

key inclusion criteria: 1. hospitalization for covid-19 infection 2. severe acute respiratory syndrome coronavirus (sars-cov)-2 infection confirmed by polymerase chain reaction (pcr) 3. cohort 1: participant requires supplemental oxygen for pulmonary distress related to covid-19 infection, and has been on supplemental oxygen for no more than 48 hours. cohort 2: participants will have been on mechanical ventilation for ≤ 24 hours from the time of screening 4. radiographic evidence of pulmonary infiltrates key

key inclusion criteria: 1. hospitalization for covid-19 infection 2. severe acute respiratory syndrome coronavirus (sars-cov)-2 infection confirmed by polymerase chain reaction (pcr) 3. cohort 1: participant requires supplemental oxygen for pulmonary distress related to covid-19 infection, and has been on supplemental oxygen for no more than 48 hours. cohort 2: participants will have been on mechanical ventilation for ≤ 24 hours from the time of screening 4. radiographic evidence of pulmonary infiltrates key