heart rate <50 beats per minute, atrioventricular conduction block of grade ii or iii, mean arterial pressure (map) <55 mmhg (despite appropriate intravenous volume replacement and vasopressor treatment), acute severe neurological disorder, propofol or dexmedetomidine allergy or other contraindications.

heart rate <50 beats per minute, atrioventricular conduction block of grade ii or iii, mean arterial pressure (map) <55 mmhg (despite appropriate intravenous volume replacement and vasopressor treatment), acute severe neurological disorder, propofol or dexmedetomidine allergy or other contraindications.