do not intubate order; pao2/fio2 ≤75 recorded at the time of consent. the pao2/fio2 can be imputed from pulse oximetry; receiving imv via endotracheal intubation or tracheostomy; receiving ecmo; shock defined by the use of vasopressors; known history of: organ or hematologic transplant; hiv; active hepatitis b, or hepatitis c infection; current treatment with: chemotherapy; immunosuppressive medications or immunotherapy (see protocol (section 5.3) for list of prohibited immunosuppressive medications and immunotherapy) at the time of consent; hemodialysis or peritoneal dialysis; known to be pregnant or is nursing; currently participating in another study of an investigational drug or therapeutic medical device at the time of consent; known allergy to eggs or any of the excipients in study drug.

do not intubate order; pao2/fio2 ≤75 recorded at the time of consent. the pao2/fio2 can be imputed from pulse oximetry; receiving imv via endotracheal intubation or tracheostomy; receiving ecmo; shock defined by the use of vasopressors; known history of: organ or hematologic transplant; hiv; active hepatitis b, or hepatitis c infection; current treatment with: chemotherapy; immunosuppressive medications or immunotherapy (see protocol (section 5.3) for list of prohibited immunosuppressive medications and immunotherapy) at the time of consent; hemodialysis or peritoneal dialysis; known to be pregnant or is nursing; currently participating in another study of an investigational drug or therapeutic medical device at the time of consent; known allergy to eggs or any of the excipients in study drug.