to be eligible for entry into the study, the subject must not meet any of the exclusion criteria listed below: age < 18 pregnant or lactating women history of heart failure clinically significant cardiac dysrhythmia, as determined by investigator history renal impairment presence of any of the following abnormal laboratory values at screening: absolute neutrophil count (anc) less than 2000 mm3, aspartate aminotransferase

to be eligible for entry into the study, the subject must not meet any of the exclusion criteria listed below: age < 18 pregnant or lactating women history of heart failure clinically significant cardiac dysrhythmia, as determined by investigator history renal impairment presence of any of the following abnormal laboratory values at screening: absolute neutrophil count (anc) less than 2000 mm3, aspartate aminotransferase