inclusion criteria: - - alert and conscious adults with the age of > 18 years old severe covid-19 pneumonia o spo2 <94% on room air at sea level, respiratory frequency >30 breaths/min, or lung infiltrates >50% - received tocilizumab within 10 days prior to enrollment - tocilizumab is co-admisnitered with a systemic corticosteroid - agree to sign conflict of interest

inclusion criteria: - - alert and conscious adults with the age of > 18 years old severe covid-19 pneumonia o spo2 <94% on room air at sea level, respiratory frequency >30 breaths/min, or lung infiltrates >50% - received tocilizumab within 10 days prior to enrollment - tocilizumab is co-admisnitered with a systemic corticosteroid - agree to sign conflict of interest