inclusion criteria: - positive sars-cov-2 test on nasopharyngeal swab - onset of symptoms <8 days prior to randomization - news score<4 and no item ≥2 - at least one comorbidity among: age ≥ 70 years old, history of cardiac disease, diabetes, obesity, chronic kidney disease, chronic respiratory failure, immunosuppression, neoplasia, liver failure (stage ≥ child-pugh b) - fully able to understand the challenges of the trial - signed informed consent - covered by health insurance

inclusion criteria: - positive sars-cov-2 test on nasopharyngeal swab - onset of symptoms <8 days prior to randomization - news score<4 and no item ≥2 - at least one comorbidity among: age ≥ 70 years old, history of cardiac disease, diabetes, obesity, chronic kidney disease, chronic respiratory failure, immunosuppression, neoplasia, liver failure (stage ≥ child-pugh b) - fully able to understand the challenges of the trial - signed informed consent - covered by health insurance