- known covid-19 positivity defined as: a laboratory confirmed case as defined by the local public health institutes - suspected covid-19 positivity defined as possessing symptoms consistent with covid-19 infections such as: headache, fever, nausea, vomiting, diarrhea, dyspnea, dry cough - healthcare workers with pre-existing retinopathy or serious visual problems - healthcare workers with known malignancies receiving active chemotherapy or immune modifying medications - healthcare workers with known autoimmune disorders - healthcare workers with known qt prolongation - history of ventricular arrhythmias - participants at risk of malignant arrythmias ○ at risk defined as: a sudden loss of consciousness with injury; anyone in their immediate family, under the age of 45year, with sudden cardiac death; anyone family history of long qt syndrome - known sensitivity/allergy to hydroxychloroquine - healthcare workers that are currently pregnant - healthcare workers that are already taking chloroquine or hydroxychloroquine - healthcare workers on colchicine or any other anti-viral medication - healthcare workers taking a medication that may interact with hydroxychloroquine (see table below - inability to take oral medications - inability to provide written consent - known g6pd deficiency

- known covid-19 positivity defined as: a laboratory confirmed case as defined by the local public health institutes - suspected covid-19 positivity defined as possessing symptoms consistent with covid-19 infections such as: headache, fever, nausea, vomiting, diarrhea, dyspnea, dry cough - healthcare workers with pre-existing retinopathy or serious visual problems - healthcare workers with known malignancies receiving active chemotherapy or immune modifying medications - healthcare workers with known autoimmune disorders - healthcare workers with known qt prolongation - history of ventricular arrhythmias - participants at risk of malignant arrythmias ○ at risk defined as: a sudden loss of consciousness with injury; anyone in their immediate family, under the age of 45year, with sudden cardiac death; anyone family history of long qt syndrome - known sensitivity/allergy to hydroxychloroquine - healthcare workers that are currently pregnant - healthcare workers that are already taking chloroquine or hydroxychloroquine - healthcare workers on colchicine or any other anti-viral medication - healthcare workers taking a medication that may interact with hydroxychloroquine (see table below - inability to take oral medications - inability to provide written consent - known g6pd deficiency