- patient with a contraindication to taking azithromycin, namely: allergy to macrolides, severe liver failure. - in combination with medicines containing cisapride, colchicine, ergotamine or dihydroergotamine - pregnant, parturient or breastfeeding women. - asymptomatic patients - patient unable to be compliant with study protocol - patient under guardianship or curators, under the protection of justice or private public law.

- patient with a contraindication to taking azithromycin, namely: allergy to macrolides, severe liver failure. - in combination with medicines containing cisapride, colchicine, ergotamine or dihydroergotamine - pregnant, parturient or breastfeeding women. - asymptomatic patients - patient unable to be compliant with study protocol - patient under guardianship or curators, under the protection of justice or private public law.