- age <18 or pregnant or lactating woman. - allergy to vitamin c. - severe liver failure. - egfr ≤ 30 ml / min / 1.73 m2 (defined by the ckd-epi scr formula). - history of any organ transplants requiring treatment active immunosuppressant that may interfere with kidney function. - if you required cardiopulmonary resuscitation (cpr) within 14 days, and/or dnr orders (do not resuscitate) dni (do not intubate). - if death is considered imminent or unavoidable during this admission, and the treating physician, patient, or surrogate decision-maker is not engaged in active treatment. - be on dialysis (either acute or chronic) or need dialysis imminent at the time of enrollment. - patients with known hiv infection. - patients with a known or suspected history of nephropathy due to oxalate or hyperoxaluria, scurvy, chronic iron overload, deficiency by g-6pd. - patients with known hemochromatosis.

- age <18 or pregnant or lactating woman. - allergy to vitamin c. - severe liver failure. - egfr ≤ 30 ml / min / 1.73 m2 (defined by the ckd-epi scr formula). - history of any organ transplants requiring treatment active immunosuppressant that may interfere with kidney function. - if you required cardiopulmonary resuscitation (cpr) within 14 days, and/or dnr orders (do not resuscitate) dni (do not intubate). - if death is considered imminent or unavoidable during this admission, and the treating physician, patient, or surrogate decision-maker is not engaged in active treatment. - be on dialysis (either acute or chronic) or need dialysis imminent at the time of enrollment. - patients with known hiv infection. - patients with a known or suspected history of nephropathy due to oxalate or hyperoxaluria, scurvy, chronic iron overload, deficiency by g-6pd. - patients with known hemochromatosis.