inclusion criteria: - understands and agrees to comply with research procedures and provides written informed consent - physical and mental health meet criteria to participate, which includes factors associated with increased risk of exposure to sars-cov-2, such as age > 65, mild to moderate obesity (bmi 30-40), hypertension controlled with medication, drug controlled hyperlipidemia, diabetes controlled with medication, mild chronic lung disease - vein access permits for blood collection - for people with reproductive ability, adequate contraception and negative pregnancy test for women

inclusion criteria: - understands and agrees to comply with research procedures and provides written informed consent - physical and mental health meet criteria to participate, which includes factors associated with increased risk of exposure to sars-cov-2, such as age > 65, mild to moderate obesity (bmi 30-40), hypertension controlled with medication, drug controlled hyperlipidemia, diabetes controlled with medication, mild chronic lung disease - vein access permits for blood collection - for people with reproductive ability, adequate contraception and negative pregnancy test for women