- hypersensitivity (peanut,eggs and soya bean) - uncontrolled hyperlipidemia - severe primary blood coagulation diseases - acute pancreatitis - acute thromboembolic diseases - liver failure (bilirubin >40 mmol/l, alanine aminotransferase >100 u/l and aspartate aminotransferase >100 u/l) - rifle (risk, injury, failure, loss of kidney function and end-stage kidney disease) stage iii and iv renal failure - pregnancy or lactation - severe neutropenia (<500 cells/mm3)

- hypersensitivity (peanut,eggs and soya bean) - uncontrolled hyperlipidemia - severe primary blood coagulation diseases - acute pancreatitis - acute thromboembolic diseases - liver failure (bilirubin >40 mmol/l, alanine aminotransferase >100 u/l and aspartate aminotransferase >100 u/l) - rifle (risk, injury, failure, loss of kidney function and end-stage kidney disease) stage iii and iv renal failure - pregnancy or lactation - severe neutropenia (<500 cells/mm3)