- retinal degeneration. - congenital or acquired long qt syndrome. - advanced liver failure. - renal insufficiency (incompatible with creatinine clearance less than 50 ml /minute). - allergic to hydroxychloroquine or azithromycin. - serious interaction with the drugs used. - pregnant or breastfeeding. - men and women in fertile and sexually active periods, who do not accept a highly effective contraceptive method. - inability to follow study procedures.

- retinal degeneration. - congenital or acquired long qt syndrome. - advanced liver failure. - renal insufficiency (incompatible with creatinine clearance less than 50 ml /minute). - allergic to hydroxychloroquine or azithromycin. - serious interaction with the drugs used. - pregnant or breastfeeding. - men and women in fertile and sexually active periods, who do not accept a highly effective contraceptive method. - inability to follow study procedures.