inclusion criteria: - adults ≥ 18 years of age - approval from the patient's primary inpatient service - hospitalized - diagnosed with covid-19 pneumonia - positive test for active sars-cov-2 infection - requiring supplemental oxygen ≥ 5lnc or ≥ 40% fio2. - chest computed tomography (ct) at admission with < 10% pulmonary fibrosis - ability to provide written informed consent on the part of the subject or, in the absence of decisional capacity of the subject, an appropriate surrogate (e.g. a legally authorized representative).

inclusion criteria: - adults ≥ 18 years of age - approval from the patient's primary inpatient service - hospitalized - diagnosed with covid-19 pneumonia - positive test for active sars-cov-2 infection - requiring supplemental oxygen ≥ 5lnc or ≥ 40% fio2. - chest computed tomography (ct) at admission with < 10% pulmonary fibrosis - ability to provide written informed consent on the part of the subject or, in the absence of decisional capacity of the subject, an appropriate surrogate (e.g. a legally authorized representative).