males and females >=18 years of age willing and able to provide written informed consent prior to performing study procedures currently hospitalized and requiring medical care for covid-19 significant covid-19 symptom, or judged by the treating provider to be at high risk of progression to severe covid-19 infection significant covid-19 symptoms are defined by one or more of the following: dyspnea respiratory frequency ≥ 30/min blood oxygen saturation ≤ 93% and one or more of the following: (positive pcr test or positive antibodies) or (ct/chest x-ray consistent with covid19 infection) or (anosmia).

males and females >=18 years of age willing and able to provide written informed consent prior to performing study procedures currently hospitalized and requiring medical care for covid-19 significant covid-19 symptom, or judged by the treating provider to be at high risk of progression to severe covid-19 infection significant covid-19 symptoms are defined by one or more of the following: dyspnea respiratory frequency ≥ 30/min blood oxygen saturation ≤ 93% and one or more of the following: (positive pcr test or positive antibodies) or (ct/chest x-ray consistent with covid19 infection) or (anosmia).

- males and females >=18 years of age - willing and able to provide written informed consent prior to performing study procedures - currently hospitalized and requiring medical care for covid-19 - significant covid-19 symptom, or judged by the treating provider to be at high risk of progression to severe covid-19 infection - significant covid-19 symptoms are defined by one or more of the following: 1. dyspnea 2. respiratory frequency ≥ 30/min 3. blood oxygen saturation ≤ 93% - and one or more of the following: (positive pcr test or positive antibodies) or (ct/chest x-ray consistent with covid19 infection) or (anosmia).

- males and females >=18 years of age - willing and able to provide written informed consent prior to performing study procedures - currently hospitalized and requiring medical care for covid-19 - significant covid-19 symptom, or judged by the treating provider to be at high risk of progression to severe covid-19 infection - significant covid-19 symptoms are defined by one or more of the following: 1. dyspnea 2. respiratory frequency ≥ 30/min 3. blood oxygen saturation ≤ 93% - and one or more of the following: (positive pcr test or positive antibodies) or (ct/chest x-ray consistent with covid19 infection) or (anosmia).