inclusion criteria: women or men of ≥ 18 years of age sars-cov-2 infection confirmed by molecular testing. admitted to the intensive care unit with pneumonia by covid-19 infection in the last 48 hours, that meet at least one of these criteria: respiratory distress. respiratory rate (fr) ≥ 30 rpm. basal oxygen saturation at rest ≤ 93%. arterial partial pressure of oxygen (pao₂) / inspiratory fraction of oxygen (fio₂) ≤300mmhg consent of the patient or his legal representative for participation in the study.

inclusion criteria: women or men of ≥ 18 years of age sars-cov-2 infection confirmed by molecular testing. admitted to the intensive care unit with pneumonia by covid-19 infection in the last 48 hours, that meet at least one of these criteria: respiratory distress. respiratory rate (fr) ≥ 30 rpm. basal oxygen saturation at rest ≤ 93%. arterial partial pressure of oxygen (pao₂) / inspiratory fraction of oxygen (fio₂) ≤300mmhg consent of the patient or his legal representative for participation in the study.

inclusion criteria: 1. women or men of ≥ 18 years of age 2. sars-cov-2 infection confirmed by molecular testing. 3. admitted to the intensive care unit with pneumonia by covid-19 infection in the last 48 hours, that meet at least one of these criteria: 1. respiratory distress. 2. respiratory rate (fr) ≥ 30 rpm. 3. basal oxygen saturation at rest ≤ 93%. 4. arterial partial pressure of oxygen (pao₂) / inspiratory fraction of oxygen (fio₂) ≤300mmhg 4. consent of the patient or his legal representative for participation in the study.

inclusion criteria: 1. women or men of ≥ 18 years of age 2. sars-cov-2 infection confirmed by molecular testing. 3. admitted to the intensive care unit with pneumonia by covid-19 infection in the last 48 hours, that meet at least one of these criteria: 1. respiratory distress. 2. respiratory rate (fr) ≥ 30 rpm. 3. basal oxygen saturation at rest ≤ 93%. 4. arterial partial pressure of oxygen (pao₂) / inspiratory fraction of oxygen (fio₂) ≤300mmhg 4. consent of the patient or his legal representative for participation in the study.