- patients with abnormal liver function (alt, ast), chronic kidney disease or dialysis (crcl< 30 ml/min) - pregnant women or women who are breastfeeding - immunocompromised patients taking medication upon screening - subjects with comorbid condition like hypertension, cardiovascular disease, diabetes mellites, asthma, copd, malignancy - patients having allergy to hydroxychloroquine and/or nitazoxanide - patients with contraindication towards the study medication including retinopathy, g6pd deficiency and qt prolongation.

- patients with abnormal liver function (alt, ast), chronic kidney disease or dialysis (crcl< 30 ml/min) - pregnant women or women who are breastfeeding - immunocompromised patients taking medication upon screening - subjects with comorbid condition like hypertension, cardiovascular disease, diabetes mellites, asthma, copd, malignancy - patients having allergy to hydroxychloroquine and/or nitazoxanide - patients with contraindication towards the study medication including retinopathy, g6pd deficiency and qt prolongation.