- intracranial hypertension - hypersensitivity to the active ingredient (propofol or sevoflurane) or to any of the excipients - current volume < 250ml - history of malignant hyperthermia - liver failure - neutropenia (<0.5x109) - pregnant or lactating women - have received chemotherapy in the last month since their inclusion in the study

- intracranial hypertension - hypersensitivity to the active ingredient (propofol or sevoflurane) or to any of the excipients - current volume < 250ml - history of malignant hyperthermia - liver failure - neutropenia (<0.5x109) - pregnant or lactating women - have received chemotherapy in the last month since their inclusion in the study