- in the opinion of the investigator, progression to death is imminent and inevitable within the next 24 hours, irrespective of the provision of treatment - participating in other drug clinical trials (participation in covid-19 antiviral trials may be permitted if approved by sponsor)* - pregnant or breastfeeding, positive pregnancy test in a pre-dose examination - any serious medical condition or abnormality of clinical laboratory tests that, in the investigator's judgment, precludes the patient's safe participation in and completion of the study

- in the opinion of the investigator, progression to death is imminent and inevitable within the next 24 hours, irrespective of the provision of treatment - participating in other drug clinical trials (participation in covid-19 antiviral trials may be permitted if approved by sponsor)* - pregnant or breastfeeding, positive pregnancy test in a pre-dose examination - any serious medical condition or abnormality of clinical laboratory tests that, in the investigator's judgment, precludes the patient's safe participation in and completion of the study