inclusion criteria: - confirmed covid-19 disease - refractory shock with need for norepinephrine ≥ 0.2 μg/kg/min for map ≥ 65 mmhg - il6 ≥ 500 ng/l - indication for crrt or ecmo

inclusion criteria: - confirmed covid-19 disease - refractory shock with need for norepinephrine ≥ 0.2 μg/kg/min for map ≥ 65 mmhg - il6 ≥ 500 ng/l - indication for crrt or ecmo