inclusion criteria: - age over 18 years - definitive proof of covid-19 infection by polymerase chain reaction (pcr) within 48 hours of hospital admission - covid-19 related moderate ards following berlin criteria definition with pao2/fio2 < 200 requiring what condition? - signed and dated informed consent form (icf) by the subject or caregivers

inclusion criteria: - age over 18 years - definitive proof of covid-19 infection by polymerase chain reaction (pcr) within 48 hours of hospital admission - covid-19 related moderate ards following berlin criteria definition with pao2/fio2 < 200 requiring what condition? - signed and dated informed consent form (icf) by the subject or caregivers