- pleural effusion > grade 2 evident on chest x-ray (cxr) or chest computed tomography (ct) - intubation/mechanical ventilation - known hypersensitivity to dasatinib - patient being treated with immunomodulators or anti-rejection drugs - known active infections or other clinical condition that contraindicate dasatinib and cannot be treated or solved according to the judgement of the clinician - alt/ast > 5 times the upper limit of the normality - total bilirubin > 3 x iuln - neutrophils < 1000 / mmc unless; platelets < 50,000 / mmc

- pleural effusion > grade 2 evident on chest x-ray (cxr) or chest computed tomography (ct) - intubation/mechanical ventilation - known hypersensitivity to dasatinib - patient being treated with immunomodulators or anti-rejection drugs - known active infections or other clinical condition that contraindicate dasatinib and cannot be treated or solved according to the judgement of the clinician - alt/ast > 5 times the upper limit of the normality - total bilirubin > 3 x iuln - neutrophils < 1000 / mmc unless; platelets < 50,000 / mmc