- pregnancy - patients with pre-existing terminal condition with life expectancy < 6 months - patients with pre-existing severe lung disease requiring home o2 - history of seizure disorder - history of adverse reaction to antihistamines or to cyproheptadine

- pregnancy - patients with pre-existing terminal condition with life expectancy < 6 months - patients with pre-existing severe lung disease requiring home o2 - history of seizure disorder - history of adverse reaction to antihistamines or to cyproheptadine