inclusion criteria: - patients included in the corimuno-19 cohort (nct04324047) - covid-19 cases not requiring icu at admission with moderate or severe pneumopathy according to the who criteria of severity of covid pneumopathy: - moderate cases: cases meeting all of the following criteria: [showing fever and respiratory symptoms with radiological findings of pneumonia] and [requiring between 3l/min and 5l/min of oxygen to maintain spo2>97%] or - severe cases: cases meeting any of the following criteria: [respiratory distress ( ≥ 30 breaths/ min)] or [oxygen saturation≤93% at rest in ambient air; or oxygen saturation ≤97 % with o2 > 5l/min] or [pao2/fio2 ≤ 300mmhg]

inclusion criteria: - patients included in the corimuno-19 cohort (nct04324047) - covid-19 cases not requiring icu at admission with moderate or severe pneumopathy according to the who criteria of severity of covid pneumopathy: - moderate cases: cases meeting all of the following criteria: [showing fever and respiratory symptoms with radiological findings of pneumonia] and [requiring between 3l/min and 5l/min of oxygen to maintain spo2>97%] or - severe cases: cases meeting any of the following criteria: [respiratory distress ( ≥ 30 breaths/ min)] or [oxygen saturation≤93% at rest in ambient air; or oxygen saturation ≤97 % with o2 > 5l/min] or [pao2/fio2 ≤ 300mmhg]