- edentulous patients, patients with low glasgow coma score, intubated, immune-compromised, history of radiotherapy or chemotherapy will be excluded. patients with known pre-existing chronic mucosal lesions such as lichen planus will also be excluded.

- edentulous patients, patients with low glasgow coma score, intubated, immune-compromised, history of radiotherapy or chemotherapy will be excluded. patients with known pre-existing chronic mucosal lesions such as lichen planus will also be excluded.