inclusion criteria: common criteria: - subjects with the ability to take the study product orally - ability to understand the study, the information about the symptoms and to comply with the treatment shots. - subject or legal guardian / representative willing to give informed consent in writing. influenza vaccine groups: - subjects who require hospitalization or external follow-up (outpatients or pades) - subjects over 60 years old who will receive the influenza vaccine covid-19 vaccine groups - subjects from long-stay centres attached to the hospital mare de déu de la mercè, and meet the following inclusion criteria: - groups: - subjects over 18 years of age who receive the covid-19 vaccine, in a stable clinical situation, at the discretion of the researcher, or - healthcare workers of the study centers, over 18 years of age who receive the covid-19 vaccine - availability to attend clinical visits.

inclusion criteria: common criteria: - subjects with the ability to take the study product orally - ability to understand the study, the information about the symptoms and to comply with the treatment shots. - subject or legal guardian / representative willing to give informed consent in writing. influenza vaccine groups: - subjects who require hospitalization or external follow-up (outpatients or pades) - subjects over 60 years old who will receive the influenza vaccine covid-19 vaccine groups - subjects from long-stay centres attached to the hospital mare de déu de la mercè, and meet the following inclusion criteria: - groups: - subjects over 18 years of age who receive the covid-19 vaccine, in a stable clinical situation, at the discretion of the researcher, or - healthcare workers of the study centers, over 18 years of age who receive the covid-19 vaccine - availability to attend clinical visits.