inclusion criteria : - aged ≥ 18 years on the day of inclusion. - a female participant is eligible to participate if she is not pregnant or breastfeeding and one of the following conditions applies: - is of non-childbearing potential. to be considered of non-childbearing potential, a female must be pre-menarche or post-menopausal for at least 1 year, or surgically sterile. or - is of childbearing potential and agrees to use an effective contraceptive method or abstinence from at least 4 weeks prior to the first vaccination until at least 12 weeks after the last vaccination. a participant of childbearing potential must have a negative highly sensitive pregnancy test (urine or serum as required by local regulation) within 8 hours before the study intervention. - informed consent form has been signed and dated. - participant not eligible to receive, based on local guidance, or if eligible does not intend to receive an authorized/approved covid-19 vaccine from first vaccination until completion of the key timepoint of day 43 of follow-up of this study.

inclusion criteria : - aged ≥ 18 years on the day of inclusion. - a female participant is eligible to participate if she is not pregnant or breastfeeding and one of the following conditions applies: - is of non-childbearing potential. to be considered of non-childbearing potential, a female must be pre-menarche or post-menopausal for at least 1 year, or surgically sterile. or - is of childbearing potential and agrees to use an effective contraceptive method or abstinence from at least 4 weeks prior to the first vaccination until at least 12 weeks after the last vaccination. a participant of childbearing potential must have a negative highly sensitive pregnancy test (urine or serum as required by local regulation) within 8 hours before the study intervention. - informed consent form has been signed and dated. - participant not eligible to receive, based on local guidance, or if eligible does not intend to receive an authorized/approved covid-19 vaccine from first vaccination until completion of the key timepoint of day 43 of follow-up of this study.

inclusion criteria : - aged ≥ 18 years on the day of inclusion. - a female participant is eligible to participate if she is not pregnant or breastfeeding and one of the following conditions applies: - is of non-childbearing potential. to be considered of non-childbearing potential, a female must be pre-menarche or post-menopausal for at least 1 year, or surgically sterile. or - is of childbearing potential and agrees to use an effective contraceptive method or abstinence from at least 4 weeks prior to the first vaccination until at least 12 weeks after the last vaccination. a participant of childbearing potential must have a negative highly sensitive pregnancy test (urine or serum as required by local regulation) within 8 hours before any dose of study intervention. - informed consent form has been signed and dated. - participant not eligible to receive, based on local guidance, or if eligible does not intend to receive an authorized/approved covid-19 vaccine from first vaccination until completion of the key timepoint of day 43 of follow-up of this study.

inclusion criteria : - aged ≥ 18 years on the day of inclusion. - a female participant is eligible to participate if she is not pregnant or breastfeeding and one of the following conditions applies: - is of non-childbearing potential. to be considered of non-childbearing potential, a female must be pre-menarche or post-menopausal for at least 1 year, or surgically sterile. or - is of childbearing potential and agrees to use an effective contraceptive method or abstinence from at least 4 weeks prior to the first vaccination until at least 12 weeks after the last vaccination. a participant of childbearing potential must have a negative highly sensitive pregnancy test (urine or serum as required by local regulation) within 8 hours before any dose of study intervention. - informed consent form has been signed and dated. - participant not eligible to receive, based on local guidance, or if eligible does not intend to receive an authorized/approved covid-19 vaccine from first vaccination until completion of the key timepoint of day 43 of follow-up of this study.