inclusion criteria: - aged 18 years or older - intubated and expected to remain invasively mechanically ventilated the day after tomorrow - laboratory confirmed covid-19 (diagnosis of sars-cov-2 via reverse transcriptase polymerase chain reaction as per the world health organization protocol or by nucleic acid based isothermal amplification)

inclusion criteria: - aged 18 years or older - intubated and expected to remain invasively mechanically ventilated the day after tomorrow - laboratory confirmed covid-19 (diagnosis of sars-cov-2 via reverse transcriptase polymerase chain reaction as per the world health organization protocol or by nucleic acid based isothermal amplification)