inclusion criteria: - covid-19 infection confirmed by pcr - new onset radiological infiltrates - respiratory failure (pao2 / fio2 <300 or sato2 / fio2 <220) - pcr>100 mg/l and/or d-dimer>1000 µg/l and/or ferritin>1000 ug/l - informed consent.

inclusion criteria: - covid-19 infection confirmed by pcr - new onset radiological infiltrates - respiratory failure (pao2 / fio2 <300 or sato2 / fio2 <220) - pcr>100 mg/l and/or d-dimer>1000 µg/l and/or ferritin>1000 ug/l - informed consent.