- patients with polytrauma, - pregnant women, - severe hemodynamic instability, - patients with pulmonary edema, - less than 3 days spent in the icu, - patients who have microbiologically proven bacterial infection on arrival.

- patients with polytrauma, - pregnant women, - severe hemodynamic instability, - patients with pulmonary edema, - less than 3 days spent in the icu, - patients who have microbiologically proven bacterial infection on arrival.