inclusion criteria: - outpatients with symptomatic laboratory-proven diagnosis of covid-19 (any exam that shows acute infection as positive pcr or igm in a context of acute symptoms ≤ 10 days) and - negative pregnancy test for women in child bearing period and - d-dimer level ≥ 2x uln or - c-reactive protein (crp) ≥ 10 mg/l or - at least two of the following risk factors: - d-dimer level ≥uln - crp ≥uln - age ≥65, - diabetes, - chronic kidney disease stage 3 - cardiopulmonary disease (for example, peripheral arterial disease, coronary artery disease, heart failure, chronic obstructive pulmonary disease), - history of pe/dvt, - nursing home/snf resident or severely restricted mobility - body mass index ≥30 kg/m2.

inclusion criteria: - outpatients with symptomatic laboratory-proven diagnosis of covid-19 (any exam that shows acute infection as positive pcr or igm in a context of acute symptoms ≤ 10 days) and - negative pregnancy test for women in child bearing period and - d-dimer level ≥ 2x uln or - c-reactive protein (crp) ≥ 10 mg/l or - at least two of the following risk factors: - d-dimer level ≥uln - crp ≥uln - age ≥65, - diabetes, - chronic kidney disease stage 3 - cardiopulmonary disease (for example, peripheral arterial disease, coronary artery disease, heart failure, chronic obstructive pulmonary disease), - history of pe/dvt, - nursing home/snf resident or severely restricted mobility - body mass index ≥30 kg/m2.