inclusion criteria: subjects 18 years of age and above with at least one risk factor for disease progression (i.e., age≥ 65, hypertension, diabetes, obesity (bmi ≥30 as defined by cdc), cancer, immunodeficiency and in the opinion of the investigator the risk factor is not acutely life-threatening). laboratory confirmed infection of sars-cov-2 within 5 days of baseline/day 1. subjects must meet the severity score of moderate or greater for two of the first ten symptoms listed in the patient reported outcomes (pro) at screening. ability to travel to clinic. ability to understand and sign an informed consent form. female subjects of child-bearing potential who are capable of conception must be: post- menopausal (one year or greater without menses), surgically incapable of childbearing, or practicing two effective methods of birth control. acceptable methods include abstinence, intrauterine device, spermicide, barrier, male partner surgical sterilization and hormonal contraception. a female subject ≥18 years of age and of child bearing potential must agree to practice two acceptable methods of birth control during the study period. ability to swallow a capsule. ability to complete an electronic diary via smartphone or web.

inclusion criteria: subjects 18 years of age and above with at least one risk factor for disease progression (i.e., age≥ 65, hypertension, diabetes, obesity (bmi ≥30 as defined by cdc), cancer, immunodeficiency and in the opinion of the investigator the risk factor is not acutely life-threatening). laboratory confirmed infection of sars-cov-2 within 5 days of baseline/day 1. subjects must meet the severity score of moderate or greater for two of the first ten symptoms listed in the patient reported outcomes (pro) at screening. ability to travel to clinic. ability to understand and sign an informed consent form. female subjects of child-bearing potential who are capable of conception must be: post- menopausal (one year or greater without menses), surgically incapable of childbearing, or practicing two effective methods of birth control. acceptable methods include abstinence, intrauterine device, spermicide, barrier, male partner surgical sterilization and hormonal contraception. a female subject ≥18 years of age and of child bearing potential must agree to practice two acceptable methods of birth control during the study period. ability to swallow a capsule. ability to complete an electronic diary via smartphone or web.

inclusion criteria: - subjects 18 years of age and older with at least one comorbidity (i.e., hypertension, diabetes, obesity, cancer, chronic renal disease, immunodeficiency and in the opinion of the investigator the comorbidity is not acutely life-threatening). - laboratory confirmed infection of sar-cov-2 within 5 days of baseline/day 1. - subjects must meet the severity score of moderate or greater for two of the first ten symptoms listed in the patient reported outcomes (pro) at screening. - ability to travel to clinic. - ability to understand and sign an informed consent form. - female subjects of child-bearing potential who are capable of conception must be: post- menopausal (one year or greater without menses), surgically incapable of childbearing, or practicing two effective methods of birth control. acceptable methods include abstinence, intrauterine device, spermicide, barrier, male partner surgical sterilization and hormonal contraception. a female subject ≥18 years of age and of child bearing potential must agree to practice two acceptable methods of birth control during the study period. - ability to swallow a capsule. - ability to complete an electronic diary via smartphone or web.

inclusion criteria: - subjects 18 years of age and older with at least one comorbidity (i.e., hypertension, diabetes, obesity, cancer, chronic renal disease, immunodeficiency and in the opinion of the investigator the comorbidity is not acutely life-threatening). - laboratory confirmed infection of sar-cov-2 within 5 days of baseline/day 1. - subjects must meet the severity score of moderate or greater for two of the first ten symptoms listed in the patient reported outcomes (pro) at screening. - ability to travel to clinic. - ability to understand and sign an informed consent form. - female subjects of child-bearing potential who are capable of conception must be: post- menopausal (one year or greater without menses), surgically incapable of childbearing, or practicing two effective methods of birth control. acceptable methods include abstinence, intrauterine device, spermicide, barrier, male partner surgical sterilization and hormonal contraception. a female subject ≥18 years of age and of child bearing potential must agree to practice two acceptable methods of birth control during the study period. - ability to swallow a capsule. - ability to complete an electronic diary via smartphone or web.

inclusion criteria: - subjects 18 years of age and older with at least one comorbidity (i.e., hypertension, diabetes, obesity, cancer, chronic renal disease, immunodeficiency and in the opinion of the investigator the comorbidity is not acutely life-threatening). - laboratory confirmed infection of sar-cov-2 within 5 days of study entry. - ability to travel to clinic. - ability to understand and sign an informed consent form. - female subjects of child-bearing potential who are capable of conception must be: post- menopausal (one year or greater without menses), surgically incapable of childbearing, or practicing two effective methods of birth control. acceptable methods include abstinence, intrauterine device, spermicide, barrier, male partner surgical sterilization and hormonal contraception. a female subject ≥18 years of age and of child bearing potential must agree to practice two acceptable methods of birth control during the study period. - ability to swallow a capsule.

inclusion criteria: - subjects 18 years of age and older with at least one comorbidity (i.e., hypertension, diabetes, obesity, cancer, chronic renal disease, immunodeficiency and in the opinion of the investigator the comorbidity is not acutely life-threatening). - laboratory confirmed infection of sar-cov-2 within 5 days of study entry. - ability to travel to clinic. - ability to understand and sign an informed consent form. - female subjects of child-bearing potential who are capable of conception must be: post- menopausal (one year or greater without menses), surgically incapable of childbearing, or practicing two effective methods of birth control. acceptable methods include abstinence, intrauterine device, spermicide, barrier, male partner surgical sterilization and hormonal contraception. a female subject ≥18 years of age and of child bearing potential must agree to practice two acceptable methods of birth control during the study period. - ability to swallow a capsule.