- allergic reaction to tranexamic acid - history or active evidence of hypercoagulation disorders including but not limited to deep vein thrombosis, pulmonary hypertension, diffuse intravascular coagulopathy - preadmission anticoagulation - history of gi bleeding - history of seizures - cardiac or other vascular stents - history of severe renal disease - history of intracranial hemorrhage

- allergic reaction to tranexamic acid - history or active evidence of hypercoagulation disorders including but not limited to deep vein thrombosis, pulmonary hypertension, diffuse intravascular coagulopathy - preadmission anticoagulation - history of gi bleeding - history of seizures - cardiac or other vascular stents - history of severe renal disease - history of intracranial hemorrhage