inclusion criteria: - primary study: male or female participants between the ages of 12 and 50 years, inclusive, at randomization. - booster study: male or female participants between the ages of 18 and 50 years, inclusive, at rerandomization. - participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent/have parent(s)/legal guardian capable of giving signed informed consent.

inclusion criteria: - primary study: male or female participants between the ages of 12 and 50 years, inclusive, at randomization. - booster study: male or female participants between the ages of 18 and 50 years, inclusive, at rerandomization. - participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent/have parent(s)/legal guardian capable of giving signed informed consent.

inclusion criteria: - male or female participants between the ages of 12 and 50 years, inclusive, at randomization. - participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent/have parent(s)/legal guardian capable of giving signed informed consent.

inclusion criteria: - male or female participants between the ages of 12 and 50 years, inclusive, at randomization. - participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent/have parent(s)/legal guardian capable of giving signed informed consent.

inclusion criteria: - male or female participants between the ages of 18 and 55 years, inclusive, at randomization. - participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent

inclusion criteria: - male or female participants between the ages of 18 and 55 years, inclusive, at randomization. - participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent