inclusion criteria: - patients 18 years and over - sars-cov2 infection confirmed by pcr - patients who do not require immediate hospitalization - signed informed consent non-inclusion criteria: - patients with hiv or hepatitis b - symptoms suggestive of a sars-cov2 infection that has been progressing for more than 7 days - asympomatic patients with unknown date of infection or date of infection>7 days - chronic hcv infection - contraindication to the use of tdf/ftc - hypersensitivity to tenofovir, to emtricitabine or to any of the excipients (especially lactose) - glomerular filtration rate <80ml / min - recent (less than 7 days) or concomitant use of nsaids or other nephrotoxic drugs (antiinfectives, immunosuppressants, allopurinol, lithium - need for hospitalization for contemporary decompensation of a comorbidity - need for hospitalization due to sars-cov2 infection: - capillary oximetry less than 95% - clinical evaluation by the investigating doctor leading to hospitalization - pregnant or breastfeeding women

inclusion criteria: - patients 18 years and over - sars-cov2 infection confirmed by pcr - patients who do not require immediate hospitalization - signed informed consent non-inclusion criteria: - patients with hiv or hepatitis b - symptoms suggestive of a sars-cov2 infection that has been progressing for more than 7 days - asympomatic patients with unknown date of infection or date of infection>7 days - chronic hcv infection - contraindication to the use of tdf/ftc - hypersensitivity to tenofovir, to emtricitabine or to any of the excipients (especially lactose) - glomerular filtration rate <80ml / min - recent (less than 7 days) or concomitant use of nsaids or other nephrotoxic drugs (antiinfectives, immunosuppressants, allopurinol, lithium - need for hospitalization for contemporary decompensation of a comorbidity - need for hospitalization due to sars-cov2 infection: - capillary oximetry less than 95% - clinical evaluation by the investigating doctor leading to hospitalization - pregnant or breastfeeding women