inclusion criteria: - ability to provide written informed consent and availability to fulfill the study requirements. - participants of either gender of aged 18 years and above. - participants with good general health as determined by the discretion of the investigator, or participants with stable medical conditions. a stable medical condition is defined as a disease not requiring significant change in therapy or hospitalization or worsening disease during the 3 months before enrolment. - for a female participant of child-bearing potential, planning to avoid becoming pregnant (use of an effective method of contraception or abstinence) from the time of study enrolment until at least eight weeks after the last vaccination. - male subjects of reproductive potential: use of condoms to ensure effective contraception with the female partner and to refrain from sperm donation from first vaccination until at least 3 months after the last vaccination. - agrees not to participate in another clinical trial at any time during the study period. - agrees not to take any covid-19 licensed vaccination for the entire duration of the study. - agrees to remain in the study area for the entire duration of the study. - willing to allow storage and future use of biological samples for future research

inclusion criteria: - ability to provide written informed consent and availability to fulfill the study requirements. - participants of either gender of aged 18 years and above. - participants with good general health as determined by the discretion of the investigator, or participants with stable medical conditions. a stable medical condition is defined as a disease not requiring significant change in therapy or hospitalization or worsening disease during the 3 months before enrolment. - for a female participant of child-bearing potential, planning to avoid becoming pregnant (use of an effective method of contraception or abstinence) from the time of study enrolment until at least eight weeks after the last vaccination. - male subjects of reproductive potential: use of condoms to ensure effective contraception with the female partner and to refrain from sperm donation from first vaccination until at least 3 months after the last vaccination. - agrees not to participate in another clinical trial at any time during the study period. - agrees not to take any covid-19 licensed vaccination for the entire duration of the study. - agrees to remain in the study area for the entire duration of the study. - willing to allow storage and future use of biological samples for future research