key inclusion criteria: - willing and able to provide written informed consent, or with a legal representative who can provide informed consent. - male or non-pregnant female adult 18-85 years of age at time of enrollment. - laboratory-confirmed sars-cov-2 infection as determined by pcr, in any specimen up to 21 days prior to randomization. - meets definition of ards according to berlin criteria. key

key inclusion criteria: - willing and able to provide written informed consent, or with a legal representative who can provide informed consent. - male or non-pregnant female adult 18-85 years of age at time of enrollment. - laboratory-confirmed sars-cov-2 infection as determined by pcr, in any specimen up to 21 days prior to randomization. - meets definition of ards according to berlin criteria. key