- patients who did not sign the informed consent. - critical patient. - patient previously bitten by a snake that was treated with equine hyperimmune serum. - patients with covid-19 on an outpatient basis. - pregnant women. - patients in hemodialysis program. - patients who have already received plasma from a convalescent covid-19 patient. - patients who were classified prior to the diagnosis of covid-19 by the treating physician as having a reserved prognosis with a short lifespan.

- patients who did not sign the informed consent. - critical patient. - patient previously bitten by a snake that was treated with equine hyperimmune serum. - patients with covid-19 on an outpatient basis. - pregnant women. - patients in hemodialysis program. - patients who have already received plasma from a convalescent covid-19 patient. - patients who were classified prior to the diagnosis of covid-19 by the treating physician as having a reserved prognosis with a short lifespan.