inclusion criteria: - age (equal or more than 18 yo) - hospitalization at conventional wards due to covid-19 related mild or moderate pneumonia (curb65<3 points; sat. o2>90%) - 3-4 points according to the who ordinal scale. - confirmed covid-19 (pcr or other validated test) - d-dimer >500 ng/ml - sign of informed consent - the patient is able, according to investigator's opinion, to deal with all the requirements of the clinical trial.

inclusion criteria: - age (equal or more than 18 yo) - hospitalization at conventional wards due to covid-19 related mild or moderate pneumonia (curb65<3 points; sat. o2>90%) - 3-4 points according to the who ordinal scale. - confirmed covid-19 (pcr or other validated test) - d-dimer >500 ng/ml - sign of informed consent - the patient is able, according to investigator's opinion, to deal with all the requirements of the clinical trial.