1) with one of the following respiratory diseases: subjects with asthma history, or cannot rule out asthma based on the diagnosis of investigator; subjects with chronic obstructive pulmonary disease (copd); subjects with following respiratory diseases such as active tuberculosis, lung cancer, sarcoidosis, pulmonary hypertension, pneumothorax, uncontrolled pleural effusion through intervention, pulmonary embolism, etc.; lung volume reduction: subjects have had lung volume reduction surgery, pulmonary lobectomy, or bronchoscopic lung volume reduction surgery. 2) subjects with pulmonary heart disease. 3) patients who are scheduled for elective surgery during the study period, such as thoracic and abdominal major surgery. 4) subjects, judged by investigators, with previous or current diseases, which may affect the participation in this study or the outcome of this study: such as cancer, diseases of heart, liver, kidney, hematopoietic system and other vital organs or systems, etc. 5) patients who have undergone surgery within 1 month prior to screening and have not fully recovered. 6) occurrence of congestive heart failure, uncontrolled or unstable angina or myocardial infarction, cerebrovascular accident, or history of pulmonary embolism within 6 months prior to screening. 7) patients with active tuberculosis infection within 12 months prior to screening. 8) pregnancy or lactating women, or women of childbearing potential not agree to either abstinence or use at least one primary form of contraception from the time of screening till the study is completed. 9) subjects with mental disorders or other conditions that are unable to cooperate effectively with the conduct of the clinical trial. 10) subjects intolerance to inhalation therapy. 11) others whom the investigator or sub-investigator judged inappropriate for participation in the study.

1) with one of the following respiratory diseases: subjects with asthma history, or cannot rule out asthma based on the diagnosis of investigator; subjects with chronic obstructive pulmonary disease (copd); subjects with following respiratory diseases such as active tuberculosis, lung cancer, sarcoidosis, pulmonary hypertension, pneumothorax, uncontrolled pleural effusion through intervention, pulmonary embolism, etc.; lung volume reduction: subjects have had lung volume reduction surgery, pulmonary lobectomy, or bronchoscopic lung volume reduction surgery. 2) subjects with pulmonary heart disease. 3) patients who are scheduled for elective surgery during the study period, such as thoracic and abdominal major surgery. 4) subjects, judged by investigators, with previous or current diseases, which may affect the participation in this study or the outcome of this study: such as cancer, diseases of heart, liver, kidney, hematopoietic system and other vital organs or systems, etc. 5) patients who have undergone surgery within 1 month prior to screening and have not fully recovered. 6) occurrence of congestive heart failure, uncontrolled or unstable angina or myocardial infarction, cerebrovascular accident, or history of pulmonary embolism within 6 months prior to screening. 7) patients with active tuberculosis infection within 12 months prior to screening. 8) pregnancy or lactating women, or women of childbearing potential not agree to either abstinence or use at least one primary form of contraception from the time of screening till the study is completed. 9) subjects with mental disorders or other conditions that are unable to cooperate effectively with the conduct of the clinical trial. 10) subjects intolerance to inhalation therapy. 11) others whom the investigator or sub-investigator judged inappropriate for participation in the study.

- 1) with one of the following respiratory diseases: 1. subjects with asthma history, or cannot rule out asthma based on the diagnosis of investigator; 2. subjects with chronic obstructive pulmonary disease (copd); 3. subjects with following respiratory diseases such as active tuberculosis, lung cancer, sarcoidosis, pulmonary hypertension, pneumothorax, uncontrolled pleural effusion through intervention, pulmonary embolism, etc.; 4. lung volume reduction: subjects have had lung volume reduction surgery, pulmonary lobectomy, or bronchoscopic lung volume reduction surgery. 2) subjects with pulmonary heart disease. 3) patients who are scheduled for elective surgery during the study period, such as thoracic and abdominal major surgery. 4) subjects, judged by investigators, with previous or current diseases, which may affect the participation in this study or the outcome of this study: such as cancer, diseases of heart, liver, kidney, hematopoietic system and other vital organs or systems, etc. 5) patients who have undergone surgery within 1 month prior to screening and have not fully recovered. 6) occurrence of congestive heart failure, uncontrolled or unstable angina or myocardial infarction, cerebrovascular accident, or history of pulmonary embolism within 6 months prior to screening. 7) patients with active tuberculosis infection within 12 months prior to screening. 8) pregnancy or lactating women, or women of childbearing potential not agree to either abstinence or use at least one primary form of contraception from the time of screening till the study is completed. 9) subjects with mental disorders or other conditions that are unable to cooperate effectively with the conduct of the clinical trial. 10) subjects intolerance to inhalation therapy. 11) others whom the investigator or sub-investigator judged inappropriate for participation in the study.

- 1) with one of the following respiratory diseases: 1. subjects with asthma history, or cannot rule out asthma based on the diagnosis of investigator; 2. subjects with chronic obstructive pulmonary disease (copd); 3. subjects with following respiratory diseases such as active tuberculosis, lung cancer, sarcoidosis, pulmonary hypertension, pneumothorax, uncontrolled pleural effusion through intervention, pulmonary embolism, etc.; 4. lung volume reduction: subjects have had lung volume reduction surgery, pulmonary lobectomy, or bronchoscopic lung volume reduction surgery. 2) subjects with pulmonary heart disease. 3) patients who are scheduled for elective surgery during the study period, such as thoracic and abdominal major surgery. 4) subjects, judged by investigators, with previous or current diseases, which may affect the participation in this study or the outcome of this study: such as cancer, diseases of heart, liver, kidney, hematopoietic system and other vital organs or systems, etc. 5) patients who have undergone surgery within 1 month prior to screening and have not fully recovered. 6) occurrence of congestive heart failure, uncontrolled or unstable angina or myocardial infarction, cerebrovascular accident, or history of pulmonary embolism within 6 months prior to screening. 7) patients with active tuberculosis infection within 12 months prior to screening. 8) pregnancy or lactating women, or women of childbearing potential not agree to either abstinence or use at least one primary form of contraception from the time of screening till the study is completed. 9) subjects with mental disorders or other conditions that are unable to cooperate effectively with the conduct of the clinical trial. 10) subjects intolerance to inhalation therapy. 11) others whom the investigator or sub-investigator judged inappropriate for participation in the study.