- previous history of ards in the last month - chronic respiratory diseases requiring long-term oxygen therapy and/or long-term respiratory assistance - allogeneic bone marrow transplantation - active cancer - liver cirrhosis with basal child and pugh of c - pulmonary fibrosis - patient with end-of-life decision - patient not expected to survive for 24 hours - patient who received an organ transplant - woman known to be pregnant or lactating - patient already enrolled in another interventional pharmacotherapy protocol on covid-19 - patient has burns to ≥15% of their total body surface area - patient is receiving extra-corporeal membrane oxygenation, high-frequency oscillatory ventilation or any form of extra-corporeal lung support - patient under tutelage

- previous history of ards in the last month - chronic respiratory diseases requiring long-term oxygen therapy and/or long-term respiratory assistance - allogeneic bone marrow transplantation - active cancer - liver cirrhosis with basal child and pugh of c - pulmonary fibrosis - patient with end-of-life decision - patient not expected to survive for 24 hours - patient who received an organ transplant - woman known to be pregnant or lactating - patient already enrolled in another interventional pharmacotherapy protocol on covid-19 - patient has burns to ≥15% of their total body surface area - patient is receiving extra-corporeal membrane oxygenation, high-frequency oscillatory ventilation or any form of extra-corporeal lung support - patient under tutelage