- life expectancy <28 days in the opinion of the treating physician - patient or legal representative is unable to provide written informed consent - symptomatic for 8 days or more - being admitted to the hospital at the informed consent procedure - known previous history of transfusion-related acute lung injury - known immunoglobulin a (iga) deficiency

- life expectancy <28 days in the opinion of the treating physician - patient or legal representative is unable to provide written informed consent - symptomatic for 8 days or more - being admitted to the hospital at the informed consent procedure - known previous history of transfusion-related acute lung injury - known immunoglobulin a (iga) deficiency