inclusion criteria: - japanese male or female participants between the ages of 20 and 85 years, inclusive, at randomization. - participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent.

inclusion criteria: - japanese male or female participants between the ages of 20 and 85 years, inclusive, at randomization. - participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures. - healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study. - capable of giving personal signed informed consent.