- pregnant women: current known pregnancy positive pregnancy test. - lactating women. - documented history of mental illnesses - multi-organ failure - severe ards (requiring ventilator support on presentation in the form of invasive or non-invasive ventilation) - septic shock - drug allergy/intolerance

- pregnant women: current known pregnancy positive pregnancy test. - lactating women. - documented history of mental illnesses - multi-organ failure - severe ards (requiring ventilator support on presentation in the form of invasive or non-invasive ventilation) - septic shock - drug allergy/intolerance