- known hypersensitivity to one of the used products of vitamin d or indigents in the drug's composition - active malignancy - hypercalcemia - granulomatous disease such as sarcoidosis - history of renal stones within the past year - pregnancy/breastfeeding, as evaluated through screening, - previous enrollment into the current study, - enrollment of the investigator, his/her family members, employees and other dependent persons,

- known hypersensitivity to one of the used products of vitamin d or indigents in the drug's composition - active malignancy - hypercalcemia - granulomatous disease such as sarcoidosis - history of renal stones within the past year - pregnancy/breastfeeding, as evaluated through screening, - previous enrollment into the current study, - enrollment of the investigator, his/her family members, employees and other dependent persons,