inclusion criteria: - above 18 years of age - have positive sars-cov-2 pcr on nasopharyngeal and/or oropharyngeal swabs - admitted in isolation ward and icu of institutes affiliated with duhs - have severe or critical covid 19 as judged by the treating physician - consent given by the patient or first degree relative

inclusion criteria: - above 18 years of age - have positive sars-cov-2 pcr on nasopharyngeal and/or oropharyngeal swabs - admitted in isolation ward and icu of institutes affiliated with duhs - have severe or critical covid 19 as judged by the treating physician - consent given by the patient or first degree relative